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Malathion, Medflies and Medicines
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 his module undertakes the study of selected
synthetic and
semisynthetic bioactive compounds containing phosphoryl or
sulfuryl groups used
for pest control or as drugs. The addition-elimination
chemistry exhibited by
these compounds will be examined in the context of
their fate in the environment
(pesticides) or in the human body
(drugs). |
6-8 (3-4 hr) labs, 8-10 class sessions
- Prerequisites: Introductory Level II
- Initial Testing: Fall '96
- Tool Kit: Structure and Bonding, Dynamics, Laboratory Procedures, Experimental Design, Laboratory Procedures, Data Analysis, Accessing Information, Communicating Results
- Topics: bonding, stereochemistry, reaction rates, catalysis and inhibition, stereoselectivity, analytical and synthitic methods, formulating the problem, computer/library searching (CA and Internet), oral and written reports
- Interdisciplinary aspects: Medicinal Chemistry, Toxicology, Ecology, Public Policy
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Contra Costa College:
Leverett Smith, lsmith@viking.dvc.edu
Diablo Valley College:
Ron Rusay, rrusay@viking.dvc.edu
Interdisciplinary consultant:
John Casida, Environmental Science, Policy, and Management, UC Berkeley |
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Description
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This module undertakes the study of selected
synthetic and
semisynthetic bioactive compounds used as drugs or for pest
control. It takes
compound uses and the addition-elimination substitution
reactions at
coordinatively unsaturated carbon, sulfur, and phosphorous
centers as unifying
themes. We will look at both the formation and the
breakdown of a variety of
medicinal and pesticidal compounds. As
interdisciplinary themes, the module
explores the role of synthetic
chemistry in modifying those personal aspects of
our environment that
affect our health and our food supply, while we modify our
human situation
via "synthetic chemical ecology". |
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Materials to be developed
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- Molecular database of organic compounds used in medicine and agriculture
- Transparencies
- Video presenting analytical techniques
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- Background readings, materials to guide class discussions and related in-class activities
- Materials to guide class discussions
- Sample homework, exams, and lab report formats
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Last modified: 10/18/00 at 2:20 PM
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