Optical Rotation: Part II
Structure & Configuration

In Part II, you will examine several chiral molecules. Some are NSAIDs and others are odorants whose olfactory properties have been studied by smell panels. Complete the form that goes with the structures in the table. Carvone is given as an example. Circle all of the chiral atoms in the general structure. Click on the images below to see the individual steroisomer of each molecule. (The 2 dimensional drawings do not show their respective stereochemistry.) Under comments, if it is an NSAID, indicate if the stereoisomer is the correct absolute configuration for the active drug (ACTIVE) or its enantiomer (NOT ACTIVE). If it is an odorant, list the type of smell, eg. MINT. Click on each molecule for its stereochemistry. For smell information refer to the handout: M. Laska and P. Teubner, Chemical Senses, 24, 161-170 (1999) and M. Laska, Chemical Senses, 29, 143-152 (2004).

 

	General Structures (Jmol links)
A
B
C
D
E
F